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Early disruption of nerve mitochondrial and myelin lipid homeostasis in obesity-induced diabetes

Diabetic neuropathy is a major complication of diabetes. Current treatment options alleviate pain but do not stop the progression of the disease. At present, there are no approved disease-modifying therapies. Thus, developing more effective therapies remains a major unmet medical need. Seeking to be...

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Detalles Bibliográficos
Autores principales: Palavicini, Juan P., Chen, Juan, Wang, Chunyan, Wang, Jianing, Qin, Chao, Baeuerle, Eric, Wang, Xinming, Woo, Jung A., Kang, David E., Musi, Nicolas, Dupree, Jeffrey L., Han, Xianlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710310/
https://www.ncbi.nlm.nih.gov/pubmed/33148881
http://dx.doi.org/10.1172/jci.insight.137286