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Total Glucosides of Paeony Alleviate Cell Apoptosis and Inflammation by Targeting the Long Noncoding RNA XIST/MicroRNA-124-3p/ITGB1 Axis in Renal Ischemia/Reperfusion Injury

OBJECTIVE: Renal ischemia/reperfusion injury (RI/RI) is the main cause of acute kidney injury. Total glucosides of paeony (TGP) are a traditional Chinese medicine. This study was aimed at exploring the role of TGP in RI/RI and its underlying mechanism of action. METHODS: Rat RI/RI models were constr...

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Detalles Bibliográficos
Autores principales: Chen, Fang, Hu, Yi, Xie, Yuetao, Zhao, Zonghui, Ma, Lin, Li, Zhili, Tan, Wanlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710434/
https://www.ncbi.nlm.nih.gov/pubmed/33299380
http://dx.doi.org/10.1155/2020/8869511