AMI, an Indazole Derivative, Improves Parkinson’s Disease by Inhibiting Tau Phosphorylation

Dopaminergic neuronal loss is the main pathological character of Parkinson’s disease (PD). Abnormal tau hyperphosphorylation will lead to dopaminergic neuronal loss. An indazole derivative 6-amino-1-methyl-indazole (AMI) successfully synthesized to inhibit tau hyperphosphorylation may exert a neurop...

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Detalles Bibliográficos
Autores principales: Mao, Zhang, Wen-ting, Zhu, Hai-tao, Wang, Hui, Yu, Shi-yi, Lan, Jiang-ping, Xu, Wen-ya, Wang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710523/
https://www.ncbi.nlm.nih.gov/pubmed/33328879
http://dx.doi.org/10.3389/fnmol.2020.00165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710523/
https://www.ncbi.nlm.nih.gov/pubmed/33328879
http://dx.doi.org/10.3389/fnmol.2020.00165

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