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Idiosyncratic epistasis creates universals in mutational effects and evolutionary trajectories

Patterns of epistasis and shapes of fitness landscapes are of wide interest because of their bearings on a number of evolutionary theories. The common phenomena of slowing fitness increases during adaptations and diminishing returns from beneficial mutations are believed to reflect a concave fitness...

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Detalles Bibliográficos
Autores principales: Lyons, Daniel M., Zou, Zhengting, Xu, Haiqing, Zhang, Jianzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710555/
https://www.ncbi.nlm.nih.gov/pubmed/32895516
http://dx.doi.org/10.1038/s41559-020-01286-y