A Blue Light-Inducible CRISPR-Cas9 System for Inhibiting Progression of Melanoma Cells

Melanoma is an aggressive skin tumor that shows a high mortality rate and level of metastasis. BRAF gene mutation (BRAF V600E) is directly related to the occurrence of melanoma. In this study, a light-inducible gene expression system was designed to control the Cas9 transcription, which could then c...

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Detalles Bibliográficos
Autores principales: Wu, Xia, Huang, Haiyan, Yu, Bo, Zhang, Jianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710612/
https://www.ncbi.nlm.nih.gov/pubmed/33330635
http://dx.doi.org/10.3389/fmolb.2020.606593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710612/
https://www.ncbi.nlm.nih.gov/pubmed/33330635
http://dx.doi.org/10.3389/fmolb.2020.606593

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