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A Blue Light-Inducible CRISPR-Cas9 System for Inhibiting Progression of Melanoma Cells
Melanoma is an aggressive skin tumor that shows a high mortality rate and level of metastasis. BRAF gene mutation (BRAF V600E) is directly related to the occurrence of melanoma. In this study, a light-inducible gene expression system was designed to control the Cas9 transcription, which could then c...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710612/ https://www.ncbi.nlm.nih.gov/pubmed/33330635 http://dx.doi.org/10.3389/fmolb.2020.606593 |