Understanding the Targeting Mechanisms of Multi-Specific Biologics in Immunotherapy with Multiscale Modeling

Immunotherapeutics are frequently associated with adverse side effects due to the elicitation of global immune modulation. To lower the risk of these side effects, recombinant DNA technology is employed to enhance the selectivity of cell targeting by genetically fusing different biomolecules, yieldi...

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Detalles Bibliográficos
Autores principales: Su, Zhaoqian, Wang, Bo, Almo, Steven C., Wu, Yinghao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710644/
https://www.ncbi.nlm.nih.gov/pubmed/33305190
http://dx.doi.org/10.1016/j.isci.2020.101835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710644/
https://www.ncbi.nlm.nih.gov/pubmed/33305190
http://dx.doi.org/10.1016/j.isci.2020.101835

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