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Overlapping variants in the blood, tissues and cell lines for patients with intracranial meningiomas are predominant in stem cell-related genes

OBJECTIVE: Bulk tissue genomic analysis of meningiomas identified common somatic mutations, however, it often excluded blood-related variants. In contrast, genomic characterisation of primary cell lines that can provide critical information regarding growth and proliferation, have been rare. In our...

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Detalles Bibliográficos
Autores principales: Hussein, Deema, Dallol, Ashraf, Quintas, Rita, Schulten, Hans-Juergen, Alomari, Mona, Baeesa, Saleh, Bangash, Mohammed, Alghamdi, Fahad, Khan, Ishaq, ElAssouli, M-Zaki Mustafa, Saka, Mohamad, Carracedo, Angel, Chaudhary, Adeel, Abuzenadah, Adel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710648/
https://www.ncbi.nlm.nih.gov/pubmed/33305042
http://dx.doi.org/10.1016/j.heliyon.2020.e05632