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Monitoring of the Complement System Status in Patients With B-Cell Malignancies Treated With Rituximab
Rituximab is a pioneering anti-CD20 monoclonal antibody that became the first-line drug used in immunotherapy of B-cell malignancies over the last twenty years. Rituximab activates the complement system in vitro, but there is an ongoing debate on the exact role of this effector mechanism in therapeu...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710700/ https://www.ncbi.nlm.nih.gov/pubmed/33329558 http://dx.doi.org/10.3389/fimmu.2020.584509 |