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Radiation-induced DNA damage and repair effects on 3D genome organization
The three-dimensional structure of chromosomes plays an important role in gene expression regulation and also influences the repair of radiation-induced DNA damage. Genomic aberrations that disrupt chromosome spatial domains can lead to diseases including cancer, but how the 3D genome structure resp...
Autores principales: | Sanders, Jacob T., Freeman, Trevor F., Xu, Yang, Golloshi, Rosela, Stallard, Mary A., Hill, Ashtyn M., San Martin, Rebeca, Balajee, Adayabalam S., McCord, Rachel Patton |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710719/ https://www.ncbi.nlm.nih.gov/pubmed/33268790 http://dx.doi.org/10.1038/s41467-020-20047-w |
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