A proof of concept ‘phase zero’ study of neurodevelopment using brain organoid models with Vis/near-infrared spectroscopy and electrophysiology

Homeostatic control of neuronal excitability by modulation of synaptic inhibition (I) and excitation (E) of the principal neurons is important during brain maturation. The fundamental features of in-utero brain development, including local synaptic E–I ratio and bioenergetics, can be modeled by cere...

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Detalles Bibliográficos
Autores principales: Dutta, Anirban, Karanth, Sneha Sudhakar, Bhattacharya, Mahasweta, Liput, Michal, Augustyniak, Justyna, Cheung, Mancheung, Stachowiak, Ewa K., Stachowiak, Michal K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710726/
https://www.ncbi.nlm.nih.gov/pubmed/33268815
http://dx.doi.org/10.1038/s41598-020-77929-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710726/
https://www.ncbi.nlm.nih.gov/pubmed/33268815
http://dx.doi.org/10.1038/s41598-020-77929-8

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