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Structural modularity of the XIST ribonucleoprotein complex

Long noncoding RNAs are thought to regulate gene expression by organizing protein complexes through unclear mechanisms. XIST controls the inactivation of an entire X chromosome in female placental mammals. Here we develop and integrate several orthogonal structure-interaction methods to demonstrate...

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Detalles Bibliográficos
Autores principales: Lu, Zhipeng, Guo, Jimmy K., Wei, Yuning, Dou, Diana R., Zarnegar, Brian, Ma, Qing, Li, Rui, Zhao, Yang, Liu, Fan, Choudhry, Hani, Khavari, Paul A., Chang, Howard Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710737/
https://www.ncbi.nlm.nih.gov/pubmed/33268787
http://dx.doi.org/10.1038/s41467-020-20040-3