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Astrocyte deletion of α2-Na/K ATPase triggers episodic motor paralysis in mice via a metabolic pathway

Familial hemiplegic migraine is an episodic neurological disorder characterized by transient sensory and motor symptoms and signs. Mutations of the ion pump α2-Na/K ATPase cause familial hemiplegic migraine, but the mechanisms by which α2-Na/K ATPase mutations lead to the migraine phenotype remain i...

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Detalles Bibliográficos
Autores principales: Smith, Sarah E., Chen, Xiaoying, Brier, Lindsey M., Bumstead, Jonathan R., Rensing, Nicholas R., Ringel, Alison E., Shin, Haewon, Oldenborg, Anna, Crowley, Jan R., Bice, Annie R., Dikranian, Krikor, Ippolito, Joseph E., Haigis, Marcia C., Papouin, Thomas, Zhao, Guoyan, Wong, Michael, Culver, Joseph P., Bonni, Azad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710756/
https://www.ncbi.nlm.nih.gov/pubmed/33268780
http://dx.doi.org/10.1038/s41467-020-19915-2