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Astrocyte deletion of α2-Na/K ATPase triggers episodic motor paralysis in mice via a metabolic pathway
Familial hemiplegic migraine is an episodic neurological disorder characterized by transient sensory and motor symptoms and signs. Mutations of the ion pump α2-Na/K ATPase cause familial hemiplegic migraine, but the mechanisms by which α2-Na/K ATPase mutations lead to the migraine phenotype remain i...
Autores principales: | Smith, Sarah E., Chen, Xiaoying, Brier, Lindsey M., Bumstead, Jonathan R., Rensing, Nicholas R., Ringel, Alison E., Shin, Haewon, Oldenborg, Anna, Crowley, Jan R., Bice, Annie R., Dikranian, Krikor, Ippolito, Joseph E., Haigis, Marcia C., Papouin, Thomas, Zhao, Guoyan, Wong, Michael, Culver, Joseph P., Bonni, Azad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710756/ https://www.ncbi.nlm.nih.gov/pubmed/33268780 http://dx.doi.org/10.1038/s41467-020-19915-2 |
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