Prospects of Directly Reprogrammed Adult Human Neurons for Neurodegenerative Disease Modeling and Drug Discovery: iN vs. iPSCs Models

A reliable disease model is critical to the study of specific disease mechanisms as well as for the discovery and development of new drugs. Despite providing crucial insights into the mechanisms of neurodegenerative diseases, translation of this information to develop therapeutics in clinical trials...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Xie, Xinyang, Hu, Jiangnan, Afreen, Kazi Sabrina, Zhang, Chun-Li, Zhuge, Qichuan, Yang, Jianjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710799/
https://www.ncbi.nlm.nih.gov/pubmed/33328842
http://dx.doi.org/10.3389/fnins.2020.546484

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710799/
https://www.ncbi.nlm.nih.gov/pubmed/33328842
http://dx.doi.org/10.3389/fnins.2020.546484

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