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Hepatocyte Growth Factor Mimetic ANG-3777 for Cardiac Surgery–Associated Acute Kidney Injury

INTRODUCTION: Nearly one-third of patients undergoing cardiac surgery involving cardiopulmonary bypass (CPB) experience cardiac surgery–associated (CSA) acute kidney injury (AKI); 5% require renal replacement therapy. ANG-3777 is a hepatocyte growth factor mimetic. In vitro, ANG-3777 reduces apoptos...

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Detalles Bibliográficos
Autores principales: Ayad, Sabry, Neylan, John F., Mayne, Tracy J., Gouveia, Deborah, Swaminathan, Madhav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710816/
https://www.ncbi.nlm.nih.gov/pubmed/33305126
http://dx.doi.org/10.1016/j.ekir.2020.09.031