Cargando…

Ubiquitin E3 Ligase c-Cbl Is a Host Negative Regulator of Nef Protein of HIV-1

Nef is an accessory protein encoded by human immunodeficiency virus type-1 (HIV-1) and plays important roles in regulating HIV-1 infection and viral replication. Interestingly, HIV-1 Nef can promote degradation of numerous host proteins to disrupt cellular antiviral immune response. However, how HIV...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Hong-Guang, Guo, Jing, Yuan, Yukang, Zuo, Yibo, Liu, Jin, Zhu, Li, Miao, Ying, Chen, Xiangjie, Jin, Lincong, Huang, Fan, Ren, Tengfei, He, Jiuyi, Shi, Weifeng, Wen, Zhenke, Zhu, Chuanwu, Zheng, Hui, Dong, Chunsheng, Qian, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710902/
https://www.ncbi.nlm.nih.gov/pubmed/33329486
http://dx.doi.org/10.3389/fmicb.2020.597972