Podophyllotoxin Exposure Causes Spindle Defects and DNA Damage-Induced Apoptosis in Mouse Fertilized Oocytes and Early Embryos

Podophyllotoxin (PPT) is a kind of lignans extracted from the roots and stems of the genus Podophyllum from the tiller family, and it has been widely used in the treatment of condyloma acuminatum, multiple superficial epithelioma in the clinics. However, PPT has been reported to be toxic and can cau...

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Detalles Bibliográficos
Autores principales: Hu, Lin-Lin, Liao, Bi-Yun, Wei, Jing-Xi, Ling, Yan-Lan, Wei, Yu-Xia, Liu, Zhong-Lin, Luo, Xiao-Qiong, Wang, Jun-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710938/
https://www.ncbi.nlm.nih.gov/pubmed/33330491
http://dx.doi.org/10.3389/fcell.2020.600521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710938/
https://www.ncbi.nlm.nih.gov/pubmed/33330491
http://dx.doi.org/10.3389/fcell.2020.600521

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