HERC1 Ubiquitin Ligase Is Required for Hippocampal Learning and Memory

Mutations in the human HERC1 E3 ubiquitin ligase protein develop intellectual disability. The tambaleante (tbl) mouse carries a HERC1 mutation characterized by cerebellar ataxia due of adult cerebellar Purkinje cells death by extensive autophagy. Our previous studies demonstrated that both the neuro...

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Detalles Bibliográficos
Autores principales: Pérez-Villegas, Eva M., Pérez-Rodríguez, Mikel, Negrete-Díaz, José V., Ruiz, Rocío, Rosa, Jose Luis, de Toledo, Guillermo Alvarez, Rodríguez-Moreno, Antonio, Armengol, José A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroanatomy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710975/
https://www.ncbi.nlm.nih.gov/pubmed/33328904
http://dx.doi.org/10.3389/fnana.2020.592797

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710975/
https://www.ncbi.nlm.nih.gov/pubmed/33328904
http://dx.doi.org/10.3389/fnana.2020.592797

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