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HERC1 Ubiquitin Ligase Is Required for Hippocampal Learning and Memory
Mutations in the human HERC1 E3 ubiquitin ligase protein develop intellectual disability. The tambaleante (tbl) mouse carries a HERC1 mutation characterized by cerebellar ataxia due of adult cerebellar Purkinje cells death by extensive autophagy. Our previous studies demonstrated that both the neuro...
Autores principales: | Pérez-Villegas, Eva M., Pérez-Rodríguez, Mikel, Negrete-Díaz, José V., Ruiz, Rocío, Rosa, Jose Luis, de Toledo, Guillermo Alvarez, Rodríguez-Moreno, Antonio, Armengol, José A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710975/ https://www.ncbi.nlm.nih.gov/pubmed/33328904 http://dx.doi.org/10.3389/fnana.2020.592797 |
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