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Case Report: Chronic Lymphocytic Leukemia With a Rare Translocation t(14;19)(q32;q13) Involving IGH/BCL3 Rearrangements: Report of Three Chinese Cases and Literature Review

BACKGROUND: A translocation t(14;19)(q32;q13) leading to a fusion of IGH and BCL3 which is a rare cytogenetic abnormality in CLL patients, has a more aggressive clinical course with a shorter time to first treatment (TTT) and worse overall survival (OS). To date, there is no literature reporting the...

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Detalles Bibliográficos
Autores principales: Li, Qinlu, Xing, Shugang, Zhang, Heng, Mao, Xia, Xiao, Min, Wei, Jia, Wang, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711105/
https://www.ncbi.nlm.nih.gov/pubmed/33330084
http://dx.doi.org/10.3389/fonc.2020.594732