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Innovative Cell-Based Therapies and Conditioning to Cure RAG Deficiency

Genetic defects in recombination activating genes (RAG) 1 and 2 cause a broad spectrum of severe immune defects ranging from early severe and repeated infections to inflammation and autoimmune manifestations. A correlation between in vitro recombination activity and immune phenotype has been describ...

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Detalles Bibliográficos
Autores principales: Villa, Anna, Capo, Valentina, Castiello, Maria Carmina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711106/
https://www.ncbi.nlm.nih.gov/pubmed/33329604
http://dx.doi.org/10.3389/fimmu.2020.607926