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Innovative Cell-Based Therapies and Conditioning to Cure RAG Deficiency
Genetic defects in recombination activating genes (RAG) 1 and 2 cause a broad spectrum of severe immune defects ranging from early severe and repeated infections to inflammation and autoimmune manifestations. A correlation between in vitro recombination activity and immune phenotype has been describ...
Autores principales: | Villa, Anna, Capo, Valentina, Castiello, Maria Carmina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711106/ https://www.ncbi.nlm.nih.gov/pubmed/33329604 http://dx.doi.org/10.3389/fimmu.2020.607926 |
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