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Characterization of G-quadruplex antibody reveals differential specificity for G4 DNA forms

Accumulating evidence suggests that human genome can fold into non-B DNA structures, when appropriate sequence and favourable conditions are present. Among these, G-quadruplexes (G4-DNA) are associated with gene regulation, chromosome fragility and telomere maintenance. Although several techniques a...

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Detalles Bibliográficos
Autores principales: Javadekar, Saniya M, Nilavar, Namrata M, Paranjape, Amita, Das, Kohal, Raghavan, Sathees C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711166/
https://www.ncbi.nlm.nih.gov/pubmed/33084858
http://dx.doi.org/10.1093/dnares/dsaa024