Cargando…

Apelin Inhibits Angiotensin II-Induced Atrial Fibrosis and Atrial Fibrillation via TGF-β1/Smad2/α-SMA Pathway

BACKGROUND: Angiotensin II (Ang II) could promote the development of atrial fibrosis in atrial fibrillation (AF). Apelin can inhibit the occurrence of myocardial fibrosis. However, the effect of apelin on Ang II-induced atrial fibrosis and subsequent AF still remains unknown. OBJECTIVE: In the prese...

Descripción completa

Detalles Bibliográficos
Autores principales: Lv, Wenkui, Zhang, Ling, Cheng, Xinchun, Wang, Hongli, Qin, Wen, Zhou, Xianhui, Tang, Baopeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711167/
https://www.ncbi.nlm.nih.gov/pubmed/33329030
http://dx.doi.org/10.3389/fphys.2020.583570