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Comparison of two ASC-derived therapeutics in an in vitro OA model: secretome versus extracellular vesicles

BACKGROUND: In the last years, several clinical trials have proved the safety and efficacy of adipose-derived stem/stromal cells (ASC) in contrasting osteoarthritis (OA). Since ASC act mainly through paracrine mechanisms, their secretome (conditioned medium, CM) represents a promising therapeutic al...

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Detalles Bibliográficos
Autores principales: Giannasi, Chiara, Niada, Stefania, Magagnotti, Cinzia, Ragni, Enrico, Andolfo, Annapaola, Brini, Anna Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711257/
https://www.ncbi.nlm.nih.gov/pubmed/33272318
http://dx.doi.org/10.1186/s13287-020-02035-5