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Comparison of two ASC-derived therapeutics in an in vitro OA model: secretome versus extracellular vesicles
BACKGROUND: In the last years, several clinical trials have proved the safety and efficacy of adipose-derived stem/stromal cells (ASC) in contrasting osteoarthritis (OA). Since ASC act mainly through paracrine mechanisms, their secretome (conditioned medium, CM) represents a promising therapeutic al...
Autores principales: | Giannasi, Chiara, Niada, Stefania, Magagnotti, Cinzia, Ragni, Enrico, Andolfo, Annapaola, Brini, Anna Teresa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711257/ https://www.ncbi.nlm.nih.gov/pubmed/33272318 http://dx.doi.org/10.1186/s13287-020-02035-5 |
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