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Graded doses of grape seed methanol extract attenuated hepato-toxicity following chronic carbamazepine treatment in male Wistar rats

AIM: This study investigated the effects of co-administration of carbamazepine (CBZ) with grape (Vitis vinifera) seed methanolic extract (GSME) on liver toxicity. METHOD: Thirty-five male rats (145−155 g) were randomized into 5 groups (n = 7) and administered with propylene glycol (PG 0.1 mL/day), C...

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Detalles Bibliográficos
Autores principales: Osuntokun, Opeyemi Samson, Olayiwola, Gbola, Atere, Tope Gafar, Adedokun, Kabiru Isola, Oladokun, Olayemi Olutobi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711278/
https://www.ncbi.nlm.nih.gov/pubmed/33304829
http://dx.doi.org/10.1016/j.toxrep.2020.11.006