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How Retroactivity Affects the Behavior of Incoherent Feedforward Loops

An incoherent feedforward loop (IFFL) is a network motif known for its ability to accelerate responses and generate pulses. It remains an open question to understand the behavior of IFFLs in contexts with high levels of retroactivity, where an upstream transcription factor binds to numerous downstre...

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Detalles Bibliográficos
Autores principales: Wang, Junmin, Belta, Calin, Isaacson, Samuel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711281/
https://www.ncbi.nlm.nih.gov/pubmed/33305173
http://dx.doi.org/10.1016/j.isci.2020.101779