Structural and Biophysical Insights into the TCRαβ Complex in Chickens

In this work, chicken HPAIV H5N1 epitope-specific TCRαβ (ch-TCRαβ) was isolated and its structure was determined. The Cα domain of ch-TCRαβ does not exhibit the typical structure of human TCRαβ, and the DE loop extends outward, resulting in close proximity between the Cα domain of ch-TCRαβ and CD3εδ...

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Detalles Bibliográficos
Autores principales: Zhang, Lijie, Liu, Yanjie, Meng, Geng, Liang, Ruiying, Zhang, Bing, Xia, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711287/
https://www.ncbi.nlm.nih.gov/pubmed/33305184
http://dx.doi.org/10.1016/j.isci.2020.101828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711287/
https://www.ncbi.nlm.nih.gov/pubmed/33305184
http://dx.doi.org/10.1016/j.isci.2020.101828

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