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Acellular Pertussis Vaccine Inhibits Bordetella pertussis Clearance from the Nasal Mucosa of Mice

Bordetella pertussis whole-cell vaccines (wP) caused a spectacular drop of global pertussis incidence, but since the replacement of wP with acellular pertussis vaccines (aP), pertussis has resurged in developed countries within 7 to 12 years of the change from wP to aP. In the mouse infection model,...

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Detalles Bibliográficos
Autores principales: Holubová, Jana, Staněk, Ondřej, Brázdilová, Ludmila, Mašín, Jiří, Bumba, Ladislav, Gorringe, Andrew R., Alexander, Frances, Šebo, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711433/
https://www.ncbi.nlm.nih.gov/pubmed/33228165
http://dx.doi.org/10.3390/vaccines8040695