The Medical Triazole Voriconazole Can Select for Tandem Repeat Variations in Azole-Resistant Aspergillus Fumigatus Harboring TR(34)/L98H Via Asexual Reproduction

Azole-resistant Aspergillus fumigatus isolates recovered at high frequency from patients, harbor mutations that are associated with variation of promoter length in the cyp51A gene. Following the discovery of the TR(34)/L98H genotype, new variations in tandem repeat (TR) length and number of repeats...

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Detalles Bibliográficos
Autores principales: Zhang, Jianhua, Zoll, Jan, Engel, Tobias, van den Heuvel, Joost, Verweij, Paul E., Debets, Alfons J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711461/
https://www.ncbi.nlm.nih.gov/pubmed/33187077
http://dx.doi.org/10.3390/jof6040277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711461/
https://www.ncbi.nlm.nih.gov/pubmed/33187077
http://dx.doi.org/10.3390/jof6040277

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