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The Medical Triazole Voriconazole Can Select for Tandem Repeat Variations in Azole-Resistant Aspergillus Fumigatus Harboring TR(34)/L98H Via Asexual Reproduction
Azole-resistant Aspergillus fumigatus isolates recovered at high frequency from patients, harbor mutations that are associated with variation of promoter length in the cyp51A gene. Following the discovery of the TR(34)/L98H genotype, new variations in tandem repeat (TR) length and number of repeats...
Autores principales: | Zhang, Jianhua, Zoll, Jan, Engel, Tobias, van den Heuvel, Joost, Verweij, Paul E., Debets, Alfons J. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711461/ https://www.ncbi.nlm.nih.gov/pubmed/33187077 http://dx.doi.org/10.3390/jof6040277 |
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