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Renal Dysfunction and Tubulopathy Induced by High-Dose Tenofovir Disoproxil Fumarate in C57BL/6 Mice

Tenofovir disoproxil fumarate (TDF) is the most preferred antiretroviral medicine in treating human immunodeficiency virus (HIV) and hepatitis B virus (HBV) infections. Recent clinical trials have reported conflicting results on renal toxicity and safety in TDF-treated patients, but reference animal...

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Detalles Bibliográficos
Autores principales: Jang, Eungyeong, Lee, Jong Kil, Inn, Kyung-Soo, Chung, Eun Kyoung, Lee, Kyung-Tae, Lee, Jang-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711546/
https://www.ncbi.nlm.nih.gov/pubmed/33096887
http://dx.doi.org/10.3390/healthcare8040417