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Flexible RSV Prefusogenic Fusion Glycoprotein Exposes Multiple Neutralizing Epitopes that May Collectively Contribute to Protective Immunity

Human respiratory syncytial virus (RSV) is a cause of lower respiratory tract infection in infants, young children, and older adults. There is no licensed vaccine and prophylactic treatment options are limited. The RSV fusion (F) glycoprotein is a target of host immunity and thus a focus for vaccine...

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Detalles Bibliográficos
Autores principales: Patel, Nita, Tian, Jing-Hui, Flores, Rhonda, Jacobson, Kelsey, Walker, Michelle, Portnoff, Alyse, Gueber-Xabier, Mimi, Massare, Michael J., Glenn, Greg, Ellingsworth, Larry, Smith, Gale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711572/
https://www.ncbi.nlm.nih.gov/pubmed/33066540
http://dx.doi.org/10.3390/vaccines8040607