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Impact of Single-Nucleotide Polymorphisms of CTLA-4, CD80 and CD86 on the Effectiveness of Abatacept in Patients with Rheumatoid Arthritis

Abatacept (ABA) is used as a first-line treatment in patients diagnosed with moderate and severe rheumatoid arthritis (RA). The interindividual response to ABA therapy is very variable in these patients. The objective of our study was therefore to investigate the role of polymorphisms of the CTLA-4,...

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Detalles Bibliográficos
Autores principales: Marquez Pete, Noelia, Maldonado Montoro, María del Mar, Pérez Ramírez, Cristina, Sánchez Martín, Almudena, Martínez de la Plata, Juan Enrique, Martínez Martínez, Fernando, Caliz Caliz, Rafael, Daddaoua, Abdelali, Ramírez Tortosa, María del Carmen, Jiménez Morales, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711575/
https://www.ncbi.nlm.nih.gov/pubmed/33187286
http://dx.doi.org/10.3390/jpm10040220