The Effects of Polyhexamethylene Biguanide (PHMB) and TLR Agonists Alone or as Polyplex Nanoparticles against Leishmania infantum Promastigotes and Amastigotes

Dogs are the main reservoir for Leishmania infantum, manifesting from a subclinical to a fatal disease. Limited treatments are available, although new antiparasitics and immunomodulators are pursued. Polyhexamethylene biguanide (PHMB) has a broad antimicrobial spectrum, including antiparasitic activ...

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Detalles Bibliográficos
Autores principales: Martínez-Orellana, Pamela, Baxarias, Marta, Good, Liam, Solano-Gallego, Laia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711591/
https://www.ncbi.nlm.nih.gov/pubmed/33202979
http://dx.doi.org/10.3390/vetsci7040179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711591/
https://www.ncbi.nlm.nih.gov/pubmed/33202979
http://dx.doi.org/10.3390/vetsci7040179

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