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Impact of Pre-Existing Immunity to Influenza on Live-Attenuated Influenza Vaccine (LAIV) Immunogenicity

During the previous influenza seasons, between 2010 and 2016, the live attenuated influenza vaccine (LAIV) provided variable efficacy against influenza in the U.S., causing the recommendation against the use of the LAIV. In striking contrast, pre-clinical studies have repeatedly demonstrated superio...

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Detalles Bibliográficos
Autores principales: Roy, Sreeja, Williams, Clare M., Wijesundara, Danushka K., Furuya, Yoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711626/
https://www.ncbi.nlm.nih.gov/pubmed/33207559
http://dx.doi.org/10.3390/vaccines8040683