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Next-Generation Pertussis Vaccines Based on the Induction of Protective T Cells in the Respiratory Tract

Immunization with current acellular pertussis (aP) vaccines protects against severe pertussis, but immunity wanes rapidly after vaccination and these vaccines do not prevent nasal colonization with Bordetella pertussis. Studies in mouse and baboon models have demonstrated that Th1 and Th17 responses...

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Detalles Bibliográficos
Autores principales: Chasaide, Caitlín Ní, Mills, Kingston H.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711671/
https://www.ncbi.nlm.nih.gov/pubmed/33096737
http://dx.doi.org/10.3390/vaccines8040621