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α-Synuclein Oligomer Detection with Aptamer Switch on Reduced Graphene Oxide Electrode

Protein aggregation of alpha-synuclein (α-Syn) is implicated in Parkinson’s disease (PD), and, thus, α-Syn aggregates are a potentially promising candidate biomarker for PD diagnosis. Here, we describe a simple and sensitive electrochemical sensor to monitor the aggregation of α-Syn for early PD dia...

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Detalles Bibliográficos
Autores principales: Jang, Seung Joo, Lee, Chang-Seuk, Kim, Tae Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711764/
https://www.ncbi.nlm.nih.gov/pubmed/32349285
http://dx.doi.org/10.3390/nano10050832