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Enhancing Top-Down Analysis Using Chromophore-Assisted Infrared Multiphoton Dissociation from (Phospho)peptides to Protein Assemblies

[Image: see text] Infrared multiphoton dissociation (IRMPD) has been used in mass spectrometry to fragment peptides and proteins, providing fragments mostly similar to collisional activation. Using the 10.6 μm wavelength of a CO(2) laser, IRMPD suffers from the relative low absorption cross-section...

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Detalles Bibliográficos
Autores principales: Greisch, Jean-François, van der Laarse, Saar A.M., Heck, Albert J.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711774/
https://www.ncbi.nlm.nih.gov/pubmed/33180479
http://dx.doi.org/10.1021/acs.analchem.0c03412