Unraveling the Hook Effect: A Comprehensive Study of High Antigen Concentration Effects in Sandwich Lateral Flow Immunoassays

[Image: see text] Sandwich lateral flow immunoassays (LFIAs) are limited at high antigen concentrations by the hook effect, leading to a contradictory decrease in the test line (T) intensity and false-negative results. The hook effect is mainly associated with the loss of T, and research focuses on...

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Detalles Bibliográficos
Autores principales: Ross, Georgina M. S., Filippini, Daniel, Nielen, Michel W. F., Salentijn, Gert IJ.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711776/
https://www.ncbi.nlm.nih.gov/pubmed/33185097
http://dx.doi.org/10.1021/acs.analchem.0c03740

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711776/
https://www.ncbi.nlm.nih.gov/pubmed/33185097
http://dx.doi.org/10.1021/acs.analchem.0c03740

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