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Evaluation of Phenotypic and Genotypic Variations of Drug Metabolising Enzymes and Transporters in Chronic Pain Patients Facing Adverse Drug Reactions or Non-Response to Analgesics: A Retrospective Study

This retrospective study evaluates the link between an adverse drug reaction (ADR) or a non-response to treatment and cytochromes P450 (CYP), P-glycoprotein (P-gp) or catechol-O-methyltransferase (COMT) activity in patients taking analgesic drugs for chronic pain. Patients referred to a pain center...

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Detalles Bibliográficos
Autores principales: Rollason, Victoria, Lloret-Linares, Célia, Lorenzini, Kuntheavy Ing, Daali, Youssef, Gex-Fabry, Marianne, Piguet, Valérie, Besson, Marie, Samer, Caroline, Desmeules, Jules
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711785/
https://www.ncbi.nlm.nih.gov/pubmed/33121061
http://dx.doi.org/10.3390/jpm10040198