Cargando…

Quantitative, High-Throughput Assays for Proteolytic Degradation of Amylin

Amylin is a pancreatic peptide hormone that regulates glucose homeostasis but also aggregates to form islet amyloid in type-2 diabetes. Given its role in both health and disease, there is renewed interest in proteolytic degradation of amylin by insulin-degrading enzyme (IDE) and other proteases. Her...

Descripción completa

Detalles Bibliográficos
Autores principales: Suire, Caitlin N., Brizuela, Monica K., Leissring, Malcolm A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711817/
https://www.ncbi.nlm.nih.gov/pubmed/33255272
http://dx.doi.org/10.3390/mps3040081