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Directed differentiation into insulin-producing cells using microRNA manipulation

Our commentary is focused on three studies that used microRNA overexpression methods for directed differentiation of stem cells into insulin-producing cells. Islet transplantation is the only cell-based therapy used to treat type 1 diabetes mellitus. However, due to the scarcity of cadaveric donors...

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Detalles Bibliográficos
Autores principales: Williams, Michael D., Joglekar, Mugdha V., Hardikar, Anandwardhan A., Wong, Wilson K. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711856/
https://www.ncbi.nlm.nih.gov/pubmed/33336012
http://dx.doi.org/10.1515/med-2020-0170