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CD163 Antibodies Inhibit PRRSV Infection via Receptor Blocking and Transcription Suppression

CD163 has been identified as the essential receptor for Porcine reproductive and respiratory syndrome (PRRSV), a major etiologic agent of pigs. Scavenger receptor cysteine-rich domain 5–9 (SRCR5–9) in CD163 was shown to be responsible for the virus interaction. In this study, monoclonal antibodies (...

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Detalles Bibliográficos
Autores principales: Xu, Huiling, Liu, Zehui, Zheng, Suya, Han, Guangwei, He, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711879/
https://www.ncbi.nlm.nih.gov/pubmed/33050150
http://dx.doi.org/10.3390/vaccines8040592