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Hmg1 Gene Mutation Prevalence in Triazole-Resistant Aspergillus fumigatus Clinical Isolates

Recently, mutations in the 3-hydroxy-3-methylglutaryl-coenzyme-A-reductase-encoding gene (hmg1), a gene involved in ergosterol production, were associated with triazole-resistance in Aspergillus fumigatus. In this study, we determined the prevalence and characteristics of hmg1 mutations in a collect...

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Detalles Bibliográficos
Autores principales: Resendiz-Sharpe, Agustin, Hokken, Margriet W. J., Mercier, Toine, Merckx, Rita, Verhagen, Kamiel, Dewitte, Lisa, Melchers, Willem J. G., Verweij, Paul E., Maertens, Johan, Lagrou, Katrien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711918/
https://www.ncbi.nlm.nih.gov/pubmed/33081232
http://dx.doi.org/10.3390/jof6040227