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IRF8 is crucial for the nicotine withdrawal-induced hyperalgesia in mice

BACKGROUND: Interferon regulatory factor 8 (IRF8) is involved in the pathogenesis of neuropathic pain. However, whether and how IRF8 can regulate the nicotine withdrawal (NTW)-induced hyperalgesia has not been clarified. METHODS: C57BL/6 mice were randomized and injected subcutaneously with saline (...

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Detalles Bibliográficos
Autores principales: Guo, Lina, Zhang, Yang, Wang, Jinping, Qi, Yingying, Zhang, Zongwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712045/
https://www.ncbi.nlm.nih.gov/pubmed/33335768
http://dx.doi.org/10.1515/tnsci-2020-0139