Priming with Recombinant BCG Expressing HTI Enhances the Magnitude and Breadth of the T-Cell Immune Responses Elicited by MVA.HTI in BALB/c Mice

The use of Mycobacterium bovis bacillus Calmette–Guérin (BCG) as a live vaccine vehicle is a promising approach for HIV-1-specific T-cell induction. In this study, we used recombinant BCG expressing HIVACAT T-cell immunogen (HTI), BCG.HTI(2auxo.int). BALB/c mice immunization with BCG.HTI(2auxo.int)...

Descripción completa

Detalles Bibliográficos
Autores principales: Saubi, Narcís, Kilpeläinen, Athina, Eto, Yoshiki, Chen, Chun-Wei, Olvera, Àlex, Hanke, Tomáš, Brander, Christian, Joseph-Munné, Joan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712201/
https://www.ncbi.nlm.nih.gov/pubmed/33202884
http://dx.doi.org/10.3390/vaccines8040678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712201/
https://www.ncbi.nlm.nih.gov/pubmed/33202884
http://dx.doi.org/10.3390/vaccines8040678

Ejemplares similares