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Development and Evaluation of Vero Cell-Derived Master Donor Viruses for Influenza Pandemic Preparedness

The embryonated egg-based platform currently produces the majority of seasonal influenza vaccines by employing a well-developed master donor virus (MDV, A/PR/8/34 (PR8)) to generate high-growth reassortants (HGRs) for A/H1N1 and A/H3N2 subtypes. Although the egg-based platform can supply enough seas...

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Detalles Bibliográficos
Autores principales: Chen, Po-Ling, Tzeng, Tsai-Teng, Hu, Alan Yung-Chih, Wang, Lily Hui-Ching, Lee, Min-Shi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712210/
https://www.ncbi.nlm.nih.gov/pubmed/33113866
http://dx.doi.org/10.3390/vaccines8040626